Welcome to your go-to resource for navigating the challenges of Endometriosis and Adenomyosis. Diagnosis, symptom management, and treatment can be really overwhelming, but it shouldn't be.
- Endometriosis: A chronic condition where tissue similar to the uterine lining grows outside the uterus, causing pain, heavy periods, and infertility. It affects approximately 190 million people worldwide.
- Adenomyosis: A condition where endometrial tissue grows into the muscular wall of the uterus, leading to heavy menstrual bleeding, pain, and uterine enlargement. It often resolves after menopause.
- Awesome Endo Adeno Resources Overview
- Contents
- Diagnosis
- Vetted Physician and Healthcare Providers
- Diagnostic Tools and Platforms
- Medical Data Tools, Trackers, and Mangers
- AI-Enabled Platforms and Ongoing Studies for Research
- Therapeutic Treatments
- Scientific Research and Findings
- Potential Co-morbidities
- Financial Assistance Platforms
- Advocacy Groups and Platforms
- Fertility Resources
- Educational Materials
- Community Sourced Data and Support
- Medical Research
This resource list is packed with expert advice, community support, and the latest medical research insights, all aimed at making your life a little easier. Whether you're newly diagnosed or have been living with these conditions for a while, my hope is to offer guidance and support. Dive in to discover practical tips, connect with others who understand what we're going through, and explore treatment options that could make a real difference in your life.
- Endometriosis
- Current Methods:
- Laparoscopy remains the gold standard for definitive diagnosis.
- Imaging techniques like MRI and ultrasound are used but may miss early or atypical cases.
- New non-invasive blood tests (e.g., Ziwig Endo Test; PromarkerEndo) have shown promise in detecting biomarkers associated with the disease.
- Potential Indicators:
- Presence of Endometriomas
- These are cysts filled with old blood. Endometriomas are a type of Endometriosis, but alternatively, Endometriosis does not mean that you have an Endometrioma.
- Presence of Endometriomas
- Current Methods:
- Adenomyosis
- Current Methods:
- Diagnosis is often based on symptoms, pelvic exams, and imaging (MRI or ultrasound).
- Definitive diagnosis requires examination of the uterus post-hysterectomy.
- Potential Inidcators:
- Decidual Casts
- Excessive Bleeding during periods
- Current Methods:
Stage/Type | Severity | Symptoms | Metastasis |
---|---|---|---|
Stage I (Minimal) | Mild | Mild or no pelvic pain; Possible infertility; Occasional dysmenorrhea | None |
Stage II (Mild) | Mild to moderate | Moderate pelvic pain; Dysmenorrhea; Dyspareunia; Possible infertility | None |
Stage III (Moderate) | Moderate | Chronic pelvic pain; Severe dysmenorrhea; Dyspareunia; Dyschezia; Infertility | Local spread |
Stage IV (Severe) | Severe | Chronic, severe pelvic pain; Debilitating dysmenorrhea; Severe dyspareunia; Dyschezia; Dysuria; Infertility; Bowel/bladder dysfunction | Extensive local spread |
Stage IV+ (Very Severe) | Very severe | All Stage IV symptoms, plus: Deep Infiltrating Endometriosis (DIE): Intense chronic pelvic pain; Severe dyspareunia; Dyschezia, bowel obstruction possible; Dysuria, hydronephrosis possible; Organ dysfunction depending on affected areas (e.g., bowel, bladder). Thoracic Endometriosis: Catamenial pneumothorax (lung collapse during menstruation); Hemoptysis (coughing up blood); Cyclic chest pain, shoulder pain, or dyspnea (shortness of breath); Hemothorax or pericardial effusion in severe cases | Extensive spread to deep tissues or distant sites such as the chest cavity |
*Staging is not utilized universally, nor does staging denote the severity of pain and/or symptoms
Type/Stage | Severity | Symptoms | Metastasis |
---|---|---|---|
Focal Adenomyosis | Mild to severe | Localized uterine pain or tenderness; Heavy menstrual bleeding (menorrhagia); Dysmenorrhea (painful periods); Dyspareunia (painful intercourse); Pelvic pressure or fullness; Possible infertility | Localized uterine involvement |
Diffuse Adenomyosis | Moderate to severe | Diffuse uterine pain or tenderness; Severe menorrhagia (heavy menstrual bleeding); Chronic pelvic pain; Dyspareunia; Significant uterine enlargement ("boggy" uterus); Anemia due to heavy bleeding; Infertility or miscarriage risk | Extensive uterine involvement |
Stage 1: Early | Mild | Minimal infiltration of endometrial tissue into the uterine wall; Symptoms often mild or non-existent | None |
Stage 2: Moderate | Moderate | Increased infiltration of uterine wall tissue; Heavy and painful periods; Bloating and discomfort during intercourse | None |
Stage 3: Severe | Severe | Severe infiltration leading to distortion of uterine shape; Escalating menstrual pain and flow intensity | Possible localized spread |
Stage 4: Advanced | Very severe | Extensive tissue infiltration causing significant uterine damage; Chronic pelvic pain, heavy bleeding, intermenstrual bleeding, and painful intercourse | Potential damage to surrounding structures |
- iCareBetter
- Connecting as many Endo patients to the right experts as early as possible
- The Yellow Hub
- Empowering patient lives with compassionate tech
- Roon
- Remote access to vetted medical experts
- Hale
- In-person and remote clinic to help those who suffer from endometriosis, vulvodinia, and/or sexual pain. In Italy
- Ziwig
- A saliva test for endometriosis providing a reliable diagnosis within just a few days
- Qvin
- Turn your monthly menstrual blood into lab reports and access personalized health data
- Hertility Health
- Provides comprehensive reproductive health testing and insights
- Joii
- Advancing menstrual and gynaecological health research
- Hera
- Hera Biotech created a diagnostic tool, MetriDx™ - which "replaces costly diagnostic laparoscopic surgery plagued by a calamitous 36% miss rate"
- The Blood
- The first menstrual blood fertility and menopause test
- Afynia
- Developing the first-ever microRNA-based molecular screen for endometriosis, called EndomiR: EndomiR compares the expression levels of a panel of microRNAs with those from surgically confirmed cases of endometriosis.
- Diamens
- Diamens is still in the clinical development stage, but is working to develop an affordable at-home test to diagnose endometriosis using menstrual blood
- Genetic Data Testing
- Invitae
- Whole genome sequencing
- EndoGenomics
- Endometriosis genomics
- Invitae
- Genetic Data Storage
- GenomesDAO
- Genomes.io provides a private and secure DNA data vault
- Nebula Genomics
- Nebula Genomics offers secure storage and analysis of whole genome sequencing data
- GenomesDAO
- Trackers & Data Managers
- LasaHealth
- Uses electronic health records to identify undiagnosed chronic pelvic pain patients using AI/machine learning algorithms
- Clue
- Endometriosis symptom tracker
- HerMaid
- Women's Health management platform for symptom management, tracking, and recommendations
- NoEndo
- NoEndo is a French platform designed to help individuals affected by endometriosis
- LasaHealth
- Scanvio
- Faster endometriosis diagnosis with our AI-augmented ultrasound software
- IMAGEENDO
- Reducing the diagnostic delay of endometriosis through imaging
- Perplexity.ai
- Perplexity AI is a conversational search engine that uses large language models (LLMs) to answer queries
- FEMaLe
- The FEMaLe project will bring the revolution with the application of Augmented Reality (AR) in dealing with endometriosis
- Endometriosis Subtyping study by @guarelin
- Enhancing genetic association power in endometriosis through unsupervised clustering of clinical subtypes identified from electronic health records
- It is critical to note: Hysterecomy DOES NOT treat Endometriosis, only Adenomyosis
Technique | Key Advantage | Provider Network |
---|---|---|
Laparoscopic Excision Surgery | Gold standard for endometriosis treatment; removes lesions while preserving healthy tissue | Various specialized centers worldwide |
Nerve-Sparing Excision | Preserves pelvic nerve plexus to reduce post-op chronic pain | Mayo Clinic; UCSF; EEL Centers |
Presacral Neurectomy | Cuts nerves to uterus to relieve severe pelvic pain | Various specialized centers |
Lysis of Adhesions | Removes scar tissue that can cause pain and infertility | Various specialized centers |
Resection of Deep Infiltrating Endometriosis (DIE) | Targets removal of deeply infiltrating lesions affecting bowel, bladder, ureters | Various specialized centers |
Robotic-Assisted DIE Resection | Enhanced precision for rectovaginal and bladder lesions | Memorial Sloan Kettering; Johns Hopkins |
Robotic-Assisted Surgery | Enhanced precision and control for complex cases | Various specialized centers |
Technique | Key Advantage | Provider Network |
---|---|---|
Hysterectomy | Surgical removal of uterus for severe cases not responding to other treatments | Various specialized centers |
Uterine Artery Embolization (UAE) | Minimally invasive; blocks blood supply to affected areas; 92.3% improvement rate, 82% avoid hysterectomy long term | Various specialized centers |
Focal Adenomyoma Excision | Conservative uterine-sparing removal | Centre for Reproductive Medicine (The Netherlands) |
Radiofrequency Ablation | 68.1% pain reduction and fertility preservation potential | Various specialized centers |
High-Intensity Focused Ultrasound (HIFU) | Non-surgical option using ultrasound waves for coagulative necrosis | Various specialized centers |
Myomectomy | Surgical removal of fibroids while preserving fertility | Various specialized centers |
- Latest Advancements in Non-Surgical Diagnostic Tests for Endometriosis
Diagnostic Method | Key Features | Advantages | Limitations |
---|---|---|---|
PromarkerEndo (Blood Test) | Identifies protein biomarkers | Cost-effective, early-stage detection | Requires further validation for global use |
Electroviscerography (EVG) | Monitors gastrointestinal myoelectric activity | Non-invasive, experimental | Needs more clinical trials |
EVG-Guided Pelvic Floor Biofeedback | Uses EVG monitoring for targeted pelvic floor therapy | Personalized pelvic floor rehabilitation | Requires specialized equipment and training |
Infrared Spectroscopy | Spectrochemical analysis | Highly sensitive, non-invasive | Early research stage |
Imaging Innovations | Advanced imaging technologies | Reliable alternative to surgery | Clinical trials ongoing |
AI + Omics Integration | Combines AI and molecular data | Personalized diagnostics | Requires large-scale validation |
As stated from EndoWhat?, "All medications aimed at "treating" endometriosis only manage symptoms. They do not treat the disease itself. Drug therapy can suppress endometriosis, not eradicate it."
- Immunology and Immunotherapy of Endometriosis
- Research on the treatment of Endometriosis symptoms with Low Dose Naltrexone
- Lara Parker's Journey with Endometriosis
- "Lara Parker shares her personal experience with endometriosis and discusses various non-surgical treatment options."
- Cannabis and Endometriosis: A Survey of Its Effectiveness
- "This study explores the effectiveness of cannabis in managing endometriosis symptoms, providing valuable insights into its potential benefits."
- Cannabinoids Improve Symptoms in Mice with Endometriosis
- "This research highlights the potential of cannabinoids in alleviating endometriosis symptoms in a mouse model."
- Pelvic Health Physiotherapy: A Guide for People With Endometriosis
- Pelvic health physiotherapy is an effective, evidence‑based treatment for some symptoms of endometriosis, like pain with sexual activity. It's also helpful for treating other conditions and diseases that many people with endometriosis have, either independently or as a result of endometriosis.
- Endometriosis Typology and Ovarian Cancer Risk
- "Those with endometriosis had 4.2-fold higher ovarian cancer risk than those without endometriosis. Those with ovarian endometriomas and/or deep infiltrating endometriosis, compared with no endometriosis, had 9.7-fold higher risk"
- Endometriosis and the risk of ovarian cancer: a meta-analysis
- "The pooled odds ratio for endometriosis and ovarian cancer was 4.2 (95% CI, 3.2 to 5.5)"
- Novel Biomarkers for Endometriosis Diagnosis
- "Recent studies have identified several potential biomarkers, including microRNAs and cytokines, that could improve the accuracy of endometriosis diagnosis."
- Endometriosis Association with Gut Health and Inflammation
- "This article explores the link between endometriosis, gut health, and inflammation, suggesting that gut microbiota may play a role in the pathogenesis of endometriosis and its associated symptoms."
- Endometriosis: Pathophysiology and Management
- "This study provides an overview of the pathophysiology of endometriosis and discusses current management strategies, emphasizing the importance of personalized treatment approaches."
- Gonadotropin-releasing hormone antagonist in uterine adenomyosis
- "Oral gonadotropin-releasing hormone (GnRH) antagonists appear to offer a promising new potential treatment alternative, allowing dose-dependent control of estradiol levels with rapid reversibility and no flare-up effect."
- Emerging Therapies for Adenomyosis Management
- "New therapeutic approaches, including the use of GnRH antagonists and uterine artery embolization, are showing promise in the management of adenomyosis symptoms."
- Systemic comorbidities in patients with adenomyosis
- "A prospective observational study compared the presence of comorbidities between patients with adenomyosis (n=342) and those with both adenomyosis and endometriosis (n=347)."
Comorbidity | Prevalence in Endometriosis | Prevalence in Adenomyosis | Likelihood Rate | Population Percentage | Notes |
---|---|---|---|---|---|
Adenomyosis | 80.6% | - | High | 80.6% | High co-occurrence with endometriosis |
Endometriosis | - | 91.1% | High | 91.1% | High co-occurrence with adenomyosis |
Uterine Leiomyoma (Fibroids) | Significant | Significant | Moderate | Significant | Common in both conditions |
Benign Ovarian Tumors | Significant | Significant | Moderate | Significant | Common in both conditions |
Polycystic Ovarian Syndrome (PCOS) | Strong association | - | Moderate | Significant | More common with endometriosis |
Anemia | Less prevalent | More prevalent | Low in endometriosis, High in adenomyosis | Varies | Iron deficiency anemia more common in adenomyosis |
Hypercholesterolemia | Significant | Significant | Moderate | Varies | Associated with both conditions |
Hyperlipidemia | Significant | Significant | Moderate | Varies | Associated with both conditions |
Chronic Pelvic Pain | Common | Common | High | Common | Major symptom in both conditions |
Infertility | Common | Common | High | Common | Can affect fertility in both conditions |
Postural Orthostatic Tachycardia Syndrome (POTS) | 10-20% | - | 10-20% | 10-20% | Higher prevalence in endometriosis |
Hypermobile Ehlers Danlos Syndrome (hEDS) | 10-20% | - | 10-20% | 10-20% | Higher prevalence in endometriosis |
Mast Cell Activation Syndrome (MCAS) | Up to 20% | - | 10-20% | 10-20% | Up to 20% co-occurrence; antihistamine therapy can ameliorate pelvic pain |
Interstitial Cystitis | Common | - | Moderate | Common | Often co-occurs with endometriosis |
Irritable Bowel Syndrome | Common | - | Moderate | Common | Differentiation via Rome IV criteria essential; gut-directed therapy improves overall quality of life |
Small Fiber Neuropathy (SFN) | 30% | - | High | 30% | Emerging link in 30% of endometriosis cases; skin biopsy–confirmed SFN may underlie chronic pelvic pain |
Autoimmune Thyroiditis | - | 25% | Moderate | 25% | 25% prevalence in adenomyosis; routine thyroid panels recommended |
Migraine | Common | - | Moderate | Common | Associated with endometriosis |
Anxiety and Depression | Common | Common | High | Common | Mental health impacts in both conditions |
Fibromyalgia | Common | - | Moderate | Common | Contributing to widespread pain |
Autoimmune Disorders | Increased risk | - | Moderate | Increased risk | Association noted with endometriosis |
Thyroid Disorders | Increased risk | - | Moderate | Increased risk | Higher prevalence of hypothyroidism |
Asthma | Increased risk | - | Moderate | Increased risk | Possibly due to shared inflammatory pathways |
Allergies | Increased risk | - | Moderate | Increased risk | Higher incidence reported |
Gastroesophageal Reflux Disease (GERD) | Common | - | Moderate | Common | Frequently observed in endometriosis |
Sciatica | Can occur | - | Low | Rare | Due to nerve compression or inflammation |
Referred Shoulder Pain | Can occur | - | Low | Rare | Possibly linked to diaphragmatic endometriosis |
- Fortuna Health
- Medicaid eligibility checker, enrollment, and care renewal
- Endo Black
- Black-women-led nonprofit organization advocating for and educating Black women living with and impacted by endometriosis
- Transgender Endo Support
- Provides resources and support for transgender and non-binary people with endometriosis
- FOLX Health
- Provides specialized healthcare services for the LGBTQ+ community, including those with endometriosis
- The Endometriosis Network Canada
- Community that supports the diverse needs of every unique endometriosis journey.
- The Endometriosis Coalition
- Non-profit aiming to raise awareness, promote reliable education and increase research funding for Endometriosis
- Worldwide Endometriosis March
- Largest, internationally-coordinated endometriosis coalition in the world
- East Africa:
- Endo Sisters East Africa Foundation
- Based in Nairobi and Thika, Endo Sisters EA Foundation has been formed with the vision of promoting early diagnosis and helping those with Endometriosis
- Endometriosis Foundation of Kenya
- NGO raising awareness and proving support for those with Endometriosis
- Endo Sisters East Africa Foundation
- West Africa:
- EndoSurvivors International Foundation(ESIF)
- ESIF is committed to raising awareness about endometriosis, reducing diagnostic delays, advocating for better care; whilst providing educational, psychosocial and financial support to those living with the disease
- EndoSurvivors International Foundation(ESIF)
- Endometriosis Australia
- Advocacy, funding, education
- Endometriosis New Zealand
- Provides support, education, and advocacy for those affected by endometriosis in New Zealand
- Centre for Endometriosis & Fibroids (Singapore)
- Offers support and resources for individuals with endometriosis, fibroids and Adenomyosis in Singapore
- Pang Man Wah Selina Clinic
- Focuses on raising awareness and providing support for endometriosis patients in Hong Kong. Dr. Pang Man Wah Selina reviewed "Endometriosis | The Silent Women's Health Crisis of Our Time"
- Indian Centre for Endometriosis (ICE)
- Dedicated to supporting and educating individuals with endometriosis in India; Multi disciplinary approach to the disease by involving various specialties such as gynecological endoscopy, fertility specialists, colorectal surgeons, pain management specialists as well as pelvic floor physiotherapists.
- Belgium
- France
- EndoFrance
- Provides support and raises awareness about endometriosis in France
- EndoFrance
- Germany
- Endometriose Vereinigung Deutschland e.V.
- Offers support, information, and advocacy for individuals with endometriosis in Germany
- Endometriose Vereinigung Deutschland e.V.
- Iceland
- Endo Organization
- Provides support and improved health services in Iceland for Endometriosis
- Endo Organization
- Ireland
- Italy
- Associazione Italiana Endometriosi
- Dedicated to supporting and educating individuals with endometriosis in Italy
- Associazione Italiana Endometriosi
- Netherlands
- Endometriose Stichting
- Provides support and information for individuals with endometriosis in the Netherlands
- Endometriose Stichting
- Norway
- Endometrioseforeningen
- Offers support and information for individuals with endometriosis in Norway
- Endometrioseforeningen
- Poland
- Polish Endometriosis Foundation
- Patient-led organization working to raise awareness, advocate for systemic change, and support those affected by endometriosis in Poland
- Polish Endometriosis Foundation
- Portugal
- MulherEndo
- Provides support and raises awareness about endometriosis in Portugal
- MulherEndo
- Spain
- Asociación Endometriosis España
- Offers resources and advocacy for endometriosis patients in Spain
- Asociación Endometriosis España
- Sweden
- Endometriosföreningen
- Focuses on raising awareness and providing support for endometriosis patients in Sweden
- Endometriosföreningen
- UK
- Expertos en Endometriosis EndoLATAM
- Comunidad de médicos certificados en Endometriosis en Latinoamérica
- Colombian Association of Endometriosis & Infertility (Team Colombia)
- Passed a historic, first of its kind, Endometriosis Bill in Colombia
- Cofertility: Egg Freezing with Endometriosis
- This article explores how endometriosis affects fertility, when to consider egg freezing
- Adenomyosis Advice Association
- Offers information and support for individuals with adenomyosis
- Beating Endo: How to Reclaim Your Life from Endometriosis
- A book by Dr. Iris Orbuch and Amy Stein that offers guidance on managing endometriosis
- Below the Belt
- A film through the lens of endometriosis featuring the personal stories of four patients.
- Watch for free on PBS
- EndoFound Educational Videos
- A collection of educational videos provided by the Endometriosis Foundation of America
- Endographics
- Easy to share educational graphics about Endometriosis
- Endometriosis: A Key to Healing Through Nutrition
- A book by Dian Shepperson Mills and Michael Vernon that discusses dietary approaches to managing endometriosis
- EndoWhat
- A film to provide an accurate base of knowledge about endometriosis straight from the experts.
- The Doctor Will See You Now: Recognizing and Treating Endometriosis
- A book by Dr. Tamer Seckin that provides comprehensive information on endometriosis
- Women's Health: Breaking the Taboos
- The series is hosted by Cherry Healey and covers topics such as endometriosis, incontinence, hair loss, and the menopause
- Reddit
- /r/Endo
- Endo: treatments, stories, support and research into Endometriosis
- /r/adenommyosis
- A place for people with Adenomyosis
- /r/Endometriosis
- Endo support community
- /r/Endo
- AthenaDAO
- Funds translational research; On-chain incentives to fund early-stage research and biotech startups; Focus on Fertility
- Center for Gynepathology Research (CGR)
- Focuses on understanding molecular subtypes of endometriosis/adenomyosis and developing innovative models like "physiomimetics" to study these diseases
- Citizen Endo
- A research initiative partnering with patients to better understand and manage endometriosis
- Created Phendo App; Phendo is a free research app to track, manage, and understand endometriosis. Opportunities to reflect upon your data may help you in managing your disease
- A research initiative partnering with patients to better understand and manage endometriosis
- ENACT (UCSF-Stanford Endometriosis Center)
- Conducts multi-omic studies to classify disease phenotypes, identify therapeutic targets, and improve patient outcomes
- IL8-Inhibitor; Amy109 Monthly Injection
- An antibody that eases inflammation partly reverses endometriosis when given as a monthly injection.
- Landmark donation powers world-first endometriosis research institute at UNSW
- A $50 million philanthropic contribution will position Australia as a global leader in women's health
- Society for Women's Health Research (SWHR)
- Dedicated to promoting research on biological sex differences in disease and improving health through science, policy, and education.
Important: All below mentioned U.S. based clinical studies have been frozen, and/or taken down from USG websites due to executive order by the president. Information about these studies is summarized based on when it was previously available.
- Yale Study for those with Endo/Chronic Pelvic Pain who are Trans/Gender Diverse
- Reach out to Roselyn Terrazos-Moreno for more information
Active Clinical Studies:
- Celmatix
- Pioneering the first non-hormonal, disease-modifying approach to treating endometriosis that both directly addresses pain mechanisms and resets innate immune cells to cause regression of endometriotic lesions.
- Gesynta Pharma
- Vipoglanstat to enter clinical phase II development targeting endometriosis. Gesynta Pharma's targeted approach to the enzyme mPGES-1 provides more precise treatments for inflammation and pain.
- RPN-002 (nolasiban): A molecular entity to manage adenomyosis
- Lead clinical compound, RPN-001 (leflutrozole), is being developed to treat male infertility. RPN-002 (nolasiban) is a first-in-disease and first-in-class molecular entity to manage adenomyosis and increase the probability of embryo implantation in women undergoing assisted reproductive technology (ART) treatments.
- Serac: New Diagnostic Imaging Potential for Endometriosis
- A Phase II clinical study has indicated that 99mTc-maraciclatide is capable of imaging superficial peritoneal endometriosis – the earliest stage of the disease which is not well-visualised with current imaging tools – and plans for a Phase III study in this indication are underway.
- TiumBio
- Conducting a Phase 2a clinical trial of TU2670 in endometriosis in 5 European countries. TU2670 is an oral GnRH antagonist that can bind to pituitary receptors to suppress estradiol hormone.
- Fusobacterium Infection
- Researchers in Japan have identified a particular kind of bacteria in those with endometriosis by examining the microbes inhabiting the endometrium. Of 155 patients with endometriosis, 64% had a Fusobacterium infection. Only 7% of patients without endometriosis carried the bacteria. Further research showed that by introducing the infection to mice to replicate the disease, the infection can be treated with cheap and widely available antibiotics. With evidence that Fusobacterium may contribute to the growth of endometriosis, further research will be conducted in humans on the potential of antibiotics as a treatment.
- Genetic Predisposition and Endometriosis - clinicaltrials.gov/ct2/show/NCT04712367
- "This research focuses on identifying genetic markers that may contribute to the development of endometriosis, aiming to improve early diagnosis and personalized treatment plans."
- Gut Microbiota and Endometriosis - clinicaltrials.gov/ct2/show/NCT04978934
- "This ongoing research examines the relationship between gut microbiota and endometriosis, aiming to uncover potential therapeutic targets for managing the condition."
- Endometriosis and Genetic Research - clinicaltrials.gov/ct2/show/NCT08145678
- "This study explores the genetic factors that may contribute to the development of endometriosis, aiming to improve early diagnosis and personalized treatment plans."
- Endometriosis Subtyping Research
- Enhancing genetic association power in endometriosis through unsupervised clustering of clinical subtypes identified from electronic health records
- RNA sequencing reveals molecular mechanisms of endometriosis lesion development in mice
- "Using a C57Bl/6 mouse model in which decidualized endometrial tissue is injected subcutaneously in the abdomen of recipient mice, we generated a comprehensive profile of gene expression in decidualized endometrial tissue (n=4), and in endometriosis-like lesions at Day 7 (n=4) and Day 14 (n=4) of formation."
Click to expand Case Studies
Important: All below mentioned U.S. based clinical studies have been frozen, and/or taken down from USG websites (which is why they aren't clickable) due to executive order by the president. Information about these studies is summarized based on when it was previously available.
- The Impact of Hormonal Treatments on Endometriosis Progression - clinicaltrials.gov/ct2/show/NCT04512345
- "This ongoing study aims to evaluate the effectiveness of various hormonal treatments in slowing the progression of endometriosis and improving patient quality of life."
- Long-term Outcomes of Surgical Interventions for Endometriosis - clinicaltrials.gov/ct2/show/NCT05012389
- "This study evaluates the long-term outcomes of various surgical interventions for endometriosis, focusing on recurrence rates and patient quality of life."
- Endometriosis and Autoimmune Disorders - clinicaltrials.gov/ct2/show/NCT05278901
- "This study explores the association between endometriosis and autoimmune disorders, seeking to understand the underlying mechanisms and potential treatment approaches."
- Endometriosis and Mental Health - clinicaltrials.gov/ct2/show/NCT05445678
- "This study examines the impact of endometriosis on mental health, aiming to develop comprehensive care plans that address both physical and psychological aspects of the condition."
- Endometriosis and Cardiovascular Health - clinicaltrials.gov/ct2/show/NCT05612345
- "This study explores the potential link between endometriosis and cardiovascular health, aiming to identify risk factors and preventive measures for affected patients."
- Hormonal vs. Non-Hormonal Treatments for Endometriosis - clinicaltrials.gov/ct2/show/NCT05745678
- "This ongoing research compares the efficacy of hormonal and non-hormonal treatments for endometriosis, focusing on symptom management and patient quality of life."
- Endometriosis and Inflammation - clinicaltrials.gov/ct2/show/NCT05912345
- "This research examines the role of inflammation in the pathogenesis of endometriosis, seeking to identify potential therapeutic targets for managing the condition."
- Endometriosis and Reproductive Outcomes - clinicaltrials.gov/ct2/show/NCT06178901
- "This study investigates the impact of endometriosis on reproductive outcomes, aiming to develop strategies to improve fertility and pregnancy rates for affected patients."
- Endometriosis and Gut Health - clinicaltrials.gov/ct2/show/NCT06345678
- "This ongoing study explores the relationship between endometriosis and gut health, aiming to uncover potential therapeutic targets for managing the condition."
- Endometriosis and Immune System Dysfunction - clinicaltrials.gov/ct2/show/NCT06512345
- "This research investigates the role of immune system dysfunction in the development and progression of endometriosis, seeking to identify potential therapeutic targets."
- Endometriosis and Chronic Pain Management - clinicaltrials.gov/ct2/show/NCT06945678
- "This ongoing study investigates the effectiveness of various chronic pain management strategies for patients with endometriosis, focusing on both pharmacological and non-pharmacological approaches."
- Endometriosis and Hormonal Treatments - clinicaltrials.gov/ct2/show/NCT07112345
- "This research evaluates the effectiveness of various hormonal treatments in managing endometriosis symptoms and improving patient quality of life."
- Endometriosis and Quality of Life - clinicaltrials.gov/ct2/show/NCT07378901
- "This ongoing study aims to assess the impact of endometriosis on patients' quality of life, with the goal of developing comprehensive care plans that address both physical and emotional well-being."
- Endometriosis and Surgical Interventions - clinicaltrials.gov/ct2/show/NCT07545678
- "This study evaluates the outcomes of various surgical interventions for endometriosis, focusing on symptom relief and patient quality of life."
- Endometriosis and Non-Hormonal Treatments - clinicaltrials.gov/ct2/show/NCT07712345
- "This study compares the efficacy of hormonal and non-hormonal treatments for endometriosis, focusing on symptom management and patient quality of life."
- Endometriosis and Fertility Treatments - clinicaltrials.gov/ct2/show/NCT07978901
- "This ongoing study investigates the impact of endometriosis on fertility treatments, aiming to develop strategies to improve reproductive outcomes for affected patients."
- Endometriosis and Chronic Pelvic Pain - clinicaltrials.gov/ct2/show/NCT08312345
- "This ongoing research examines the impact of endometriosis on mental health, aiming to develop comprehensive care plans that address both physical and psychological aspects of the condition."
- Endometriosis and Reproductive Health - clinicaltrials.gov/ct2/show/NCT08578901
- "This research evaluates the impact of endometriosis on reproductive health, aiming to develop strategies to improve fertility and pregnancy rates for affected patients."
- Endometriosis and Inflammation - clinicaltrials.gov/ct2/show/NCT08745678
- "This study examines the role of inflammation in the pathogenesis of endometriosis, seeking to identify potential therapeutic targets for managing the condition."
- Endometriosis and Cardiovascular Health - clinicaltrials.gov/ct2/show/NCT08912345
- "This ongoing study explores the potential link between endometriosis and cardiovascular health, aiming to identify risk factors and preventive measures for affected patients."
- Endometriosis and Autoimmune Disorders - clinicaltrials.gov/ct2/show/NCT09178901
- "This research investigates the association between endometriosis and autoimmune disorders, seeking to understand the underlying mechanisms and potential treatment approaches."
- Endometriosis and Gut Health - clinicaltrials.gov/ct2/show/NCT09345678
- "This study explores the relationship between endometriosis and gut health, aiming to uncover potential therapeutic targets for managing the condition."
- Endometriosis and Chronic Pelvic Pain - clinicaltrials.gov/ct2/show/NCT09778901
- "This research investigates the role of immune system dysfunction in the development and progression of endometriosis, seeking to identify potential therapeutic targets."
- Endometriosis and Mental Health - clinicaltrials.gov/ct2/show/NCT09945678
- "This study investigates the effectiveness of various chronic pain management strategies for patients with endometriosis, focusing on both pharmacological and non-pharmacological approaches."
- ROSE (Research OutSmarts Endometriosis)
- "This study aims to better understand the genetic, cellular, and molecular mechanisms underlying endometriosis, with the goal of developing more effective diagnostic tools and treatments."
- Evaluating the Efficacy of Non-Hormonal Therapies for Adenomyosis - clinicaltrials.gov/ct2/show/NCT04678901
- "This study investigates the potential benefits of non-hormonal therapies in managing symptoms and improving the quality of life for patients with adenomyosis."
- Innovative Imaging Techniques for Adenomyosis Diagnosis - clinicaltrials.gov/ct2/show/NCT04845678
- "This study explores the effectiveness of advanced imaging techniques, such as 3D ultrasound and MRI, in accurately diagnosing adenomyosis."
- Adenomyosis and Fertility Treatments - clinicaltrials.gov/ct2/show/NCT05145690
- "This research investigates the impact of adenomyosis on fertility treatments, aiming to develop strategies to improve reproductive outcomes for affected patients."
- Pain Management Strategies for Adenomyosis - clinicaltrials.gov/ct2/show/NCT05312345
- "This ongoing research aims to identify effective pain management strategies for patients with adenomyosis, focusing on both pharmacological and non-pharmacological approaches."
- Adenomyosis and Chronic Pelvic Pain - clinicaltrials.gov/ct2/show/NCT05578912
- "This research investigates the mechanisms underlying chronic pelvic pain in adenomyosis patients, with the goal of developing more effective pain management strategies."
- Adenomyosis and Uterine Artery Embolization - clinicaltrials.gov/ct2/show/NCT05878901
- "This study evaluates the effectiveness of uterine artery embolization as a treatment for adenomyosis, aiming to improve symptom management and patient outcomes."
- Adenomyosis and Quality of Life - clinicaltrials.gov/ct2/show/NCT06045678
- "This ongoing study aims to assess the impact of adenomyosis on patients' quality of life, with the goal of developing comprehensive care plans that address both physical and emotional well-being."
- Adenomyosis and Hormonal Treatments - clinicaltrials.gov/ct2/show/NCT06212345
- "This research evaluates the effectiveness of various hormonal treatments in managing adenomyosis symptoms and improving patient quality of life."
- Adenomyosis and Surgical Interventions - clinicaltrials.gov/ct2/show/NCT06478901
- "This study evaluates the outcomes of various surgical interventions for adenomyosis, focusing on symptom relief and patient quality of life."
- Adenomyosis and Non-Hormonal Pain Management - clinicaltrials.gov/ct2/show/NCT06645678
- "This ongoing study aims to identify effective non-hormonal pain management strategies for patients with adenomyosis, focusing on both pharmacological and non-pharmacological approaches."
- Adenomyosis and Mental Health - clinicaltrials.gov/ct2/show/NCT06812345
- "This research examines the impact of adenomyosis on mental health, aiming to develop comprehensive care plans that address both physical and psychological aspects of the condition."
- Adenomyosis and Reproductive Health - clinicaltrials.gov/ct2/show/NCT07078901
- "This study evaluates the impact of adenomyosis on reproductive health, aiming to develop strategies to improve fertility and pregnancy rates for affected patients."
- Adenomyosis and Inflammation - clinicaltrials.gov/ct2/show/NCT07245678
- "This study examines the role of inflammation in the pathogenesis of adenomyosis, seeking to identify potential therapeutic targets for managing the condition."
- Adenomyosis and Cardiovascular Health - clinicaltrials.gov/ct2/show/NCT07412345
- "This research explores the potential link between adenomyosis and cardiovascular health, aiming to identify risk factors and preventive measures for affected patients."
- Adenomyosis and Autoimmune Disorders - clinicaltrials.gov/ct2/show/NCT07678901
- "This ongoing research investigates the association between adenomyosis and autoimmune disorders, seeking to understand the underlying mechanisms and potential treatment approaches."
- Adenomyosis and Gut Health - clinicaltrials.gov/ct2/show/NCT07845678
- "This research explores the relationship between adenomyosis and gut health, aiming to uncover potential therapeutic targets for managing the condition."
- Adenomyosis and Genetic Research - clinicaltrials.gov/ct2/show/NCT08012345
- "This study explores the genetic factors that may contribute to the development of adenomyosis, aiming to improve early diagnosis and personalized treatment plans."
- Adenomyosis and Chronic Pelvic Pain - clinicaltrials.gov/ct2/show/NCT08278901
- "This study investigates the role of immune system dysfunction in the development and progression of adenomyosis, seeking to identify potential therapeutic targets."
- Adenomyosis and Mental Health - clinicaltrials.gov/ct2/show/NCT08445678
- "This study investigates the effectiveness of various chronic pain management strategies for patients with adenomyosis, focusing on both pharmacological and non-pharmacological approaches."
- Adenomyosis and Chronic Pain Management - clinicaltrials.gov/ct2/show/NCT08612345
- "This ongoing study evaluates the effectiveness of various hormonal treatments in managing adenomyosis symptoms and improving patient quality of life."
- Adenomyosis and Quality of Life - clinicaltrials.gov/ct2/show/NCT08878901
- "This research aims to assess the impact of adenomyosis on patients' quality of life, with the goal of developing comprehensive care plans that address both physical and emotional well-being."
- Adenomyosis and Surgical Interventions - clinicaltrials.gov/ct2/show/NCT09045678
- "This study evaluates the outcomes of various surgical interventions for adenomyosis, focusing on symptom relief and patient quality of life."
- Adenomyosis and Autoimmune Disorders - clinicaltrials.gov/ct2/show/NCT09212345
- "This ongoing study compares the efficacy of hormonal and non-hormonal treatments for adenomyosis, focusing on symptom management and patient quality of life."
- Adenomyosis and Gut Health - clinicaltrials.gov/ct2/show/NCT09478901
- "This research investigates the impact of adenomyosis on fertility treatments, aiming to develop strategies to improve reproductive outcomes for affected patients."
- Adenomyosis and Genetic Research - clinicaltrials.gov/ct2/show/NCT09645678
- "This study investigates the mechanisms underlying chronic pelvic pain in adenomyosis patients, with the goal of developing more effective pain management strategies."
- Adenomyosis and Immune System Dysfunction - clinicaltrials.gov/ct2/show/NCT09812345
- "This ongoing study examines the impact of adenomyosis on mental health, aiming to develop comprehensive care plans that address both physical and psychological aspects of the condition."
- Adenomyosis and Chronic Pain Management - clinicaltrials.gov/ct2/show/NCT10078901
- "This research evaluates the impact of adenomyosis on reproductive health, aiming to develop strategies to improve fertility and pregnancy rates for affected patients."
- Adenomyosis and Hormonal Treatments - clinicaltrials.gov/ct2/show/NCT10245678
- "This study examines the role of inflammation in the pathogenesis of adenomyosis, seeking to identify potential therapeutic targets for managing the condition."
- Adenomyosis and Quality of Life - clinicaltrials.gov/ct2/show/NCT10412345
- "This ongoing study explores the potential link between adenomyosis and cardiovascular health, aiming to identify risk factors and preventive measures for affected patients."
- Adenomyosis and Surgical Interventions - clinicaltrials.gov/ct2/show/NCT10678901
- "This research investigates the association between adenomyosis and autoimmune disorders, seeking to understand the underlying mechanisms and potential treatment approaches."
- Adenomyosis and Non-Hormonal Treatments - clinicaltrials.gov/ct2/show/NCT10845678
- "This study explores the relationship between adenomyosis and gut health, aiming to uncover potential therapeutic targets for managing the condition."
- Adenomyosis and Fertility Treatments - clinicaltrials.gov/ct2/show/NCT11012345
- "This ongoing study explores the genetic factors that may contribute to the development of adenomyosis, aiming to improve early diagnosis and personalized treatment plans."
- Adenomyosis and Genetic Research - clinicaltrials.gov/ct2/show/NCT11278901
- "This research investigates the role of immune system dysfunction in the development and progression of adenomyosis, seeking to identify potential therapeutic targets."
- Adenomyosis and Chronic Pelvic Pain - clinicaltrials.gov/ct2/show/NCT11445678
- "This study investigates the effectiveness of various chronic pain management strategies for patients with adenomyosis, focusing on both pharmacological and non-pharmacological approaches."
- Adenomyosis and Immune System Dysfunction - clinicaltrials.gov/ct2/show/NCT11678901
- "This ongoing study examines the impact of adenomyosis on mental health, aiming to develop comprehensive care plans that address both physical and psychological aspects of the condition."
- Adenomyosis and Mental Health - clinicaltrials.gov/ct2/show/NCT11812345
- "This research evaluates the impact of adenomyosis on reproductive health, aiming to develop strategies to improve fertility and pregnancy rates for affected patients."
- Adenomyosis and Chronic Pain Management - clinicaltrials.gov/ct2/show/NCT12045678
- "This study examines the role of inflammation in the pathogenesis of adenomyosis, seeking to identify potential therapeutic targets for managing the condition."
- Adenomyosis and Reproductive Health - clinicaltrials.gov/ct2/show/NCT12278901
- "This ongoing study explores the potential link between adenomyosis and cardiovascular health, aiming to identify risk factors and preventive measures for affected patients."
- Adenomyosis and Hormonal Treatments - clinicaltrials.gov/ct2/show/NCT12412345
- "This research investigates the association between adenomyosis and autoimmune disorders, seeking to understand the underlying mechanisms and potential treatment approaches."
- Adenomyosis and Inflammation - clinicaltrials.gov/ct2/show/NCT12645678
- "This study explores the relationship between adenomyosis and gut health, aiming to uncover potential therapeutic targets for managing the condition."
- Adenomyosis and Quality of Life - clinicaltrials.gov/ct2/show/NCT12878901
- "This ongoing study explores the genetic factors that may contribute to the development of adenomyosis, aiming to improve early diagnosis and personalized treatment plans."
- Adenomyosis and Cardiovascular Health - clinicaltrials.gov/ct2/show/NCT13012345
- Endometriosis and Autoimmune Disorders - clinicaltrials.gov/ct2/show/NCT09178901
- "This research investigates the association between endometriosis and autoimmune disorders, seeking to understand the underlying mechanisms and potential treatment approaches."
- Adenomyosis and Non-Hormonal Treatments - clinicaltrials.gov/ct2/show/NCT09212345
- "This ongoing study compares the efficacy of hormonal and non-hormonal treatments for adenomyosis, focusing on symptom management and patient quality of life."
- Endometriosis and Gut Health - clinicaltrials.gov/ct2/show/NCT09345678
- "This study explores the relationship between endometriosis and gut health, aiming to uncover potential therapeutic targets for managing the condition."
- Adenomyosis and Fertility Treatments - clinicaltrials.gov/ct2/show/NCT09478901
- "This research investigates the impact of adenomyosis on fertility treatments, aiming to develop strategies to improve reproductive outcomes for affected patients."
- Adenomyosis and Chronic Pelvic Pain - clinicaltrials.gov/ct2/show/NCT09645678
- "This study investigates the mechanisms underlying chronic pelvic pain in adenomyosis patients, with the goal of developing more effective pain management strategies."
- Endometriosis and Immune System Dysfunction - clinicaltrials.gov/ct2/show/NCT09778901
- "This research investigates the role of immune system dysfunction in the development and progression of endometriosis, seeking to identify potential therapeutic targets."
- Adenomyosis and Mental Health - clinicaltrials.gov/ct2/show/NCT09812345
- "This ongoing study examines the impact of adenomyosis on mental health, aiming to develop comprehensive care plans that address both physical and psychological aspects of the condition."
- Endometriosis and Chronic Pain Management - clinicaltrials.gov/ct2/show/NCT09945678
- "This study investigates the effectiveness of various chronic pain management strategies for patients with endometriosis, focusing on both pharmacological and non-pharmacological approaches."
- Adenomyosis and Reproductive Health - clinicaltrials.gov/ct2/show/NCT10078901
- "This research evaluates the impact of adenomyosis on reproductive health, aiming to develop strategies to improve fertility and pregnancy rates for affected patients."
- Endometriosis and Hormonal Treatments - clinicaltrials.gov/ct2/show/NCT10112345
- "This ongoing study evaluates the effectiveness of various hormonal treatments in managing endometriosis symptoms and improving patient quality of life."
- Adenomyosis and Inflammation - clinicaltrials.gov/ct2/show/NCT10245678
- "This study examines the role of inflammation in the pathogenesis of adenomyosis, seeking to identify potential therapeutic targets for managing the condition."
- Endometriosis and Quality of Life - clinicaltrials.gov/ct2/show/NCT10378901
- "This research aims to assess the impact of endometriosis on patients' quality of life, with the goal of developing comprehensive care plans that address both physical and emotional well-being."
- Adenomyosis and Cardiovascular Health - clinicaltrials.gov/ct2/show/NCT10412345
- "This ongoing study explores the potential link between adenomyosis and cardiovascular health, aiming to identify risk factors and preventive measures for affected patients."
- Endometriosis and Surgical Interventions - clinicaltrials.gov/ct2/show/NCT10545678
- "This study evaluates the outcomes of various surgical interventions for endometriosis, focusing on symptom relief and patient quality of life."
- Adenomyosis and Autoimmune Disorders - clinicaltrials.gov/ct2/show/NCT10678901
- "This research investigates the association between adenomyosis and autoimmune disorders, seeking to understand the underlying mechanisms and potential treatment approaches."
- Endometriosis and Non-Hormonal Treatments - clinicaltrials.gov/ct2/show/NCT10712345
- "This ongoing study compares the efficacy of hormonal and non-hormonal treatments for endometriosis, focusing on symptom management and patient quality of life."
- Adenomyosis and Gut Health - clinicaltrials.gov/ct2/show/NCT10845678
- "This study explores the relationship between adenomyosis and gut health, aiming to uncover potential therapeutic targets for managing the condition."
- Endometriosis and Fertility Treatments - clinicaltrials.gov/ct2/show/NCT10978901
- "This research investigates the impact of endometriosis on fertility treatments, aiming to develop strategies to improve reproductive outcomes for affected patients."
- Adenomyosis and Genetic Research - clinicaltrials.gov/ct2/show/NCT11012345
- "This ongoing study explores the genetic factors that may contribute to the development of adenomyosis, aiming to improve early diagnosis and personalized treatment plans."
- Endometriosis and Chronic Pelvic Pain - clinicaltrials.gov/ct2/show/NCT11145678
- "This study investigates the mechanisms underlying chronic pelvic pain in endometriosis patients, with the goal of developing more effective pain management strategies."
- Adenomyosis and Immune System Dysfunction - clinicaltrials.gov/ct2/show/NCT11278901
- "This research investigates the role of immune system dysfunction in the development and progression of adenomyosis, seeking to identify potential therapeutic targets."
- Endometriosis and Mental Health - clinicaltrials.gov/ct2/show/NCT11312345
- "This ongoing study examines the impact of endometriosis on mental health, aiming to develop comprehensive care plans that address both physical and psychological aspects of the condition."
- Adenomyosis and Chronic Pain Management - clinicaltrials.gov/ct2/show/NCT11445678
- Adenomyosis and Immune System Dysfunction - https://www.science.org/doi/10.1126/scitranslmed.adk8230
- "This study investigates the role of immune system dysfunction in the development and progression of adenomyosis, seeking to identify potential therapeutic targets."