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Identifying Genetic Regulatory Variants that Affect Transcription Factor Activity

This repository contatins the core code associated with the manuscript "Identifying Genetic Regulatory Variants that Affect Transcription Factor Activity."

Outline

Inferring individual-specific transcription factor activity

Scripts used for the first step can be found in the folder TF_activity_inference
Tutorial: link

Mapping genetic determinants of TF activity (aQTLs)

Scripts used for the second step can be found in the folder aQTL_mapping
Documentation: link

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